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Reboxetine mesylate
CAS No. 98769-84-7
Reboxetine mesylate( Davedax | Edronax | FCE 20124 | PNU 155950E )
Catalog No. M16899 CAS No. 98769-84-7
Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
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| 10MG | 66 | In Stock |
|
| 25MG | 149 | In Stock |
|
| 50MG | 275 | In Stock |
|
| 100MG | 439 | In Stock |
|
| 500MG | 954 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameReboxetine mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionReboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.
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DescriptionReboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.(In Vitro):Reboxetine mesylate has weak affinity for muscarinic, histaminergic H1, adrenergic α1, and dopaminergic D2 receptors.Reboxetine mesylate preventes the Dexamethasone-induced decreases in cell viability and proliferation rate.(In Vivo):Reboxetine mesylate (30 mg/kg; i.p.) significantly decreases the immobility time in the mice depression models.
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In VitroReboxetine mesylate has weak affinity for muscarinic, histaminergic H1, adrenergic α1, and dopaminergic D2 receptors.Reboxetine mesylate preventes the Dexamethasone-induced decreases in cell viability and proliferation rate. Cell Viability Assay Cell Line:SH-SY5Y cells Concentration:0.1 μM, 1 μM, 5 μM Incubation Time:24 hours Result:Prevented the Dexamethasone-induced decreases in cell viability and proliferation rate.
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In VivoReboxetine mesylate (30 mg/kg; i.p.) significantly decreases the immobility time in the mice depression models. Animal Model:Harlan-bred, male CF-1 mice (18-20 g), depression models Dosage:3 mg/kg, 30 mg/kg Administration:Intraperitoneal injection Result:Significantly decreased the immobility time in the mouse tail suspension test at the dose of 30 mg/kg.
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SynonymsDavedax | Edronax | FCE 20124 | PNU 155950E
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PathwayNeuroscience
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TargetNorepinephrine
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Recptornorepinephrine reuptake
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number98769-84-7
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Formula Weight409.5
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Molecular FormulaC19H23NO3·CH4O3S
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Purity>98% (HPLC)
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SolubilityEthanol: <1 mg/mL DMSO: 82 mg/mL (200.24 mM) Water: 82 mg/mL (200.24 mM)
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SMILESCCOC1=CC=CC=C1OC(C2CNCCO2)C3=CC=CC=C3.CS(=O)(=O)O
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Chemical Name(2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine;methanesulfonic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wong EH, et al. Biol Psychiatry, 2000, 47(9), 818-829.
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